The Global Power of Oncology Nursing (GPON) conference is held annually as part of London Global Cancer Week, showcasing the nursing contribution to tackling the global burden of cancer. Nurses share their stories, engage in debates, and celebrate their achievements with colleagues from around the world. Most nurse presenters live and work in low- and middle-income countries (LMIC) and focus on solutions to improve cancer care in a world where universal health coverage is far from a reality. Nurses can and do make a huge impact on the burden of cancer, often being the first and only point of care in their communities. However, there is a huge shortage of trained oncology nursing workforce, affecting both the work nurses can do and patient care.